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Understanding Skin Longevity: A New Paradigm of Beauty


For decades, the conversation around aging focused solely on correcting visible signs on the surface. Today, Lancôme introduces a profound shift in how we approach the passage of time. Longevity is no longer a distant ideal, but a tangible reality. It represents the opportunity to live beautifully while maintaining cellular vitality, strength, and resilience.

In this new paradigm, your skin is a living mirror of your individual healthspan. While chronological age remains fixed, your skin's visible biological age is dynamic. It represents a reality that you can actively measure and influence. By decoding the biological mechanisms of the skin, skincare becomes a powerful pillar of longevity science. This allows you to proactively optimize your skin's visible aging trajectory for a future of enduring vitality.

Woman with hydrated skin, demonstrating the benefits of skincare for dry and sensitive skin


The Science of Longevity Integrative Science™


At the heart of this revolution is Longevity Integrative Science™. Developed by leading researchers and backed by more than 20 years of longevity research, this proactive approach decodes aging mechanisms to support natural renewal.

To map these complex pathways, Lancôme utilizes the Longevity AI Cloud. This advanced system maps 267 biomarkers to reveal nine biological hallmarks of skin aging. These hallmarks are organized into the Longevity Wheel, which categorizes the aging trajectory into three functional stages:

  • Structural functions: These represent the earliest phase of aging, which often occurs before visible signs appear on the surface.
  • Metabolic functions: As cells gradually lose their functional capacity, early signs of aging begin to appear.
  • Signaling functions: This marks the later stage when tissue communication is disrupted, leading to more established visible aging cues.

By understanding these distinct stages, Lancôme has developed targeted intervention models. Developed in collaboration with longevity experts, the Absolue Longevity MD collection proactively supports skin strength, vitality, and radiance over time.



The Power of Mitochondrial Energy and Mitopure™


To preserve skin performance, we must look to the cellular engines that power renewal. Mitochondria drive 80% of cellular energy production, renewal, and resilience. However, as the skin ages, mitochondrial efficiency naturally declines, leading to a visible loss of vitality.

To address this, Lancôme introduces Mitopure™ by Timeline. This breakthrough active ingredient is a 98.5% pure and micronized form of Urolithin-A. It is an expert-recommended longevity supplement ingredient, now deployed for the first time at a global scale in advanced skincare. Mitopure™ is shown to help stimulate the natural mitochondrial recycling process, helping to support cellular energy and performance.

This unprecedented technology is the result of more than $50 Million in R&D investment and 15 years of research by leading scientists. Through a strategic partnership with Swiss longevity biotech Timeline, Lancôme translates this high-performance molecule into luxurious topical formulas that support skin health at its root.

Lancome Advanced Genifique serum with hyaluronic acid


Calibrated Interventions for Your Skin's Journey


Because your skin's needs evolve over time, a single approach is no longer enough. The Absolue Longevity MD range offers three precisely calibrated intervention models infused with Mitopure™ and proprietary compounds.

1. ANTICIPATE (Under 35 Years)

Designed for younger skin, this model focuses on proactively preserving your skin's youthful potential. The ANTICIPATE compound combines protective flavonoids, skin-recognizable sugars, and amino-acid derivatives. It helps protect the skin from everyday stressors and supports resilience.

  • Helps deliver a -16% reduction in incoming fine lines.¹
  • Supports a -50% reduction in incoming skin oxidation.²

2. INTERCEPT (Chronological Age 35 to 55)

As cellular aging begins to accelerate, the INTERCEPT compound helps support the skin's natural renewal capacity. Formulated with a complex of amino-acid building blocks, an NAD+ precursor, skin-recognizable sugars, and amino-acid derivatives, it intercepts visible signs of aging.

  • Visibly supports +25% firmer skin after just four hours.³
  • Helps promote the renewal of +3 million new surface skin cells per day.⁴

3. RESET (Chronological Age Over 55)

For mature skin where visible signs are established, the RESET compound supports deep skin recovery. This blend of signaling, biomimetic, and skin-recognizable sugars, an NAD+ precursor, and amino-acid derivatives helps restore vitality.

  • Helps achieve +41% bouncier skin.⁵
  • Supports the generation of +3 million new surface skin cells per day.⁶

Lancome Advanced Genifique serum with hyaluronic acid

Frequently Asked Questions


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